TP53 and psoriasis: By combining the main biological function of pathway and its FDR value, and p-value, we selected 5 KEGG pathways ranked by FDR value: Vascular smooth muscle contraction (FDR = 0.135, p-value = 0.034), Melanogenesis (FDR = 0.136, p-value = 0.012), Glycosphingolipid biosynthesis ganglio-series (FDR = 0.137, p-value = 0.006), Glycosaminoglycan biosynthesis keratan sulfate (FDR = 0.159, p-value = 0.01), and P53 signaling pathway (FDR = 0.180, p-value = 0.006) in psoriasis.