CD274 and breast cancer: As shown in Table 5 univariate and multivariate analyses, the PD-L1 protein expression in tumor cells was related to favorable DFS (HR=0.648, 95%CI: 0.442-0.952, P=0.027; HR=0.605, 95%CI: 0.411-0.891, P=0.011) and OS (HR=0.573, 95%CI: 0.335-0.979, P=0.042; HR=0.528, 95%CI: 0.359-0.777, P=0.001) survival of breast cancer patients.