In addition, Xu et al. surveyed that the expression level of the ABCA1 gene was significantly decreased in hypertensive patients who were newly diagnosed but untreated; Yamada et al. found that the −14C->T polymorphism of the ABCA1 gene had been appreciably affiliated with the prevalence of hypertension in Japanese individuals (17, 18). The gene discussed is ABCA1; the disease is Hypertension.