CGA increased the mRNA levels of peroxisome proliferator-activated receptor gamma (PPARγ), Liver X Receptor α (LXRα), ATP Binding Cassette Subfamily A Member 1 (ABCA1), and ATP Binding Cassette Subfamily G Member 1 (ABCG1) as well as the transcriptional activity of PPARγ, resulting in an effective reduction of ApoE−/− development of atherosclerosis in mice and promote cholesterol efflux from RAW264.7 macrophages [32, 33]. The gene discussed is APOE; the disease is atherosclerosis.