LAMC2 and lung adenocarcinoma: Studies have found that LAMC2 expression is significantly upregulated in lung adenocarcinoma metastatic cells, and high expression of LAMC2 can increase the metastasis and invasion of lung adenocarcinoma cells through epithelial mesenchymal transition (EMT), while knockdown of LAMC2 expression can reduce the metastasis and invasion of lung adenocarcinoma cells [4].