In this manner they found that the combination of resveratrol with 5-FU generated greater inhibition of the invasion capacity of HCT116 and HCT116R, even in the presence of TNF-β; moreover, this combination produced the modulation of the proinflammatory NF-κB pathway, causing sensitization of the colon cancer cells to treatment with 5-FU [7]. This evidence concerns the gene LTA and colonic neoplasm.