This was demonstrated by a greater expression and activation of caspase 3 and 8, RIPK3 (Receptor Interacting Serine/Threonine Kinase 3) and MLKL (Mixed Lineage Kinase Domain Like Pseudokinase), in OVCAR3 and three primary ovarian cancer cell lines derived from patients [47]. The gene discussed is RIPK3; the disease is ovarian carcinoma.