First, a total of 21 well-recognized m6A regulators were obtained once the RNA-seq data of ACC patients had been downloaded from the datasets, including the following 8 m6A writers: RBM15B, RBM15, ZC3H13, WTAP VIRMA, METTL16, METTL14, and METTL3; 11 readers: IGFBP1/2/3, LRPPRC, YTHDC1/2, RBMX, YTHDF1/2/3, HNRNPA2B1, FMR1, and HNRNPC, and two erasers: FTO and ALKBH5. The gene discussed is METTL16; the disease is adrenal cortex carcinoma.