As a result, we predicted 170 pharmacological targets of PC in the treatment of HF, and the resultant top 10 key genes were obtained, including TP53, RELA, CTNNB1, MAPK1, AKT1, NFKB1, FOXO3, MYC, MAPK8, and TNF. This evidence concerns the gene MAPK1 and hydrops fetalis.