As a result, we predicted 170 pharmacological targets of PC in the treatment of HF, and the resultant top 10 key genes were obtained, including TP53, RELA, CTNNB1, MAPK1, AKT1, NFKB1, FOXO3, MYC, MAPK8, and TNF. The gene discussed is MAPK8; the disease is hydrops fetalis.