As a result, we predicted 170 pharmacological targets of PC in the treatment of HF, and the resultant top 10 key genes were obtained, including TP53, RELA, CTNNB1, MAPK1, AKT1, NFKB1, FOXO3, MYC, MAPK8, and TNF. The gene discussed is TP53; the disease is hydrops fetalis.