HAVCR1 and acute kidney injury: In contrast, urinary KIM-1 measured 12 h after cardiac surgery predicted AKI with good performance (AUC-ROC 0.83–0.88), (50, 51) and a high cut-off for urinary KIM-1 (highest vs. lowest tertile) was associated with a doubling of 3-year mortality risk, independent of post-operative AKI (52).