TIMP2 and acute kidney injury: Small studies have demonstrated urinary [TIMP2]•[IGFBP7] predict AKI after cardiac surgery (AUC-ROC 0.84), (71) and in acute HF, where it outperformed KIM-1 (AUC-ROC 0.75, 0.61–0.88 vs. 0.54, 0.37–0.70) (72).