In individuals with BRAFwt melanomas, an increase in baseline and average 25(OH)D s.c. of 1 ng/ml was associated with a significantly reduced s.c. of LDH (Table 3; -3.619 U/l—baseline, p = 0.133; -5.98 U/l—during the complete OP, p = 0.016; respectively) and S100P (Table 3; -0.038 μg/l—baseline, p = 0.114; -0.058 μg/l—during the complete OP, p = 0.075, respectively). Here, S100P is linked to melanoma.