Among them, 10 genes (BAK, BAX, CASP8, CHMP2A, CHMP4C, CSCY, GSDMA, GSDMB, TP53, and ZBP1) were upregulated, whereas 15 genes (CASP1, CHMP2B, CHMP3, CHMP7, ELANE, GSDMD, GSDME, HMGB1, IL18, ILα, ILβ, IRF2, NLRP1, NLRP9, and TP63) were downregulated in the cancer tissues. Here, CASP8 is linked to cancer.