LDHB and osteosarcoma: Furthermore, LDHB expression is elevated in different types of tumors, such as triple-negative breast cancer (42), thyroid cancer (44), laryngeal squamous cell carcinoma (45), lung adenocarcinoma (14), bladder transitional cell carcinoma (46), osteosarcoma (47), testicular germ cell tumor (48) and colorectal cancer (49).