However, the inflammatory response in COVID-19 still shares some common signatures with the inflammatory response in LPS-induced RAW264.7 cells, among which the most typical are TLR4, NF-κB, and other signaling pathways and their corresponding cytokines (including IL-6, TNF, IL-1β, etc.)(Figure 2D). Here, NFKB1 is linked to COVID-19.