CASR and idiopathic type 1 diabetes: Thus, the variants with an AF greater than 50% in Europeans included SLC12A1 (n = 2), which is associated with BS type 1; CLCNKA (n = 3), which is associated with BS type 4B; CLCNKB (n = 5), which is associated with BS type 4B; and CASR (n = 2), which is associated with ADH.