DDIT3 and Alzheimer disease: Berberine regulates the mRNA levels of glucose-regulated protein 78 (GRP78), CCAAT/enhancer binding protein (C/EBP) -homologous protein (CHOP), procaspase-3/9/12 in Alzheimer’s disease rat’s hippocampus, which involve in the endoplasmic reticulum stress pathway (Xuan et al., 2020).