CXCR2 and atrial fibrillation: In contrast, inhibition of the CXCR2-MAPK (mitogen-activated protein kinase) and nicotinamide adenine dinucleotide phosphoroxidase, NF-κB, and TGFβ-1/Smad2/3 pathways significantly attenuated atrial infiltration in monocytes/macrophages, AF induction, and atrial remodelling in Ang II-infused mice (Zhang et al., 2020).