Intraductal papillary mucinous neoplasm (IPMN) is a common precancerous lesion of the pancreas, characterized by intraductal papillary proliferation of mucin-producing cells, resulting in cystic dilatation of the pancreatic duct (PD)1, 2. This evidence concerns the gene MUC5AC and pancreatic intraductal papillary-mucinous neoplasm.