AGO2 and small cell lung carcinoma: We subsequently predicted that potential miRNAs might bind to circVAPA and confirmed the interaction between circVAPA and miR-377-3p/miR-494-3p by various approaches, such as RNA pull-down assay, Ago2 RIP assay in circVAPA over-expressed SCLC cells, and dual-luciferase reporter assay.