We observed clonotypes shared between blood (effector memory) and dysfunctional CD8+ T cell clusters (for example, clonotype 187), normal adjacent tissue/nondysfunctional tumor clusters (resident memory) and dysfunctional CD8+ T cell clusters (for example, clonotype 56), as well as among the three tissues (for example, clonotype 237) (Extended Data Fig. 7d,e). The gene discussed is CD8A; the disease is neoplasm.