As reflected by RT-qPCR and Western blot analysis, EZH2 expression was decreased in GIST-T1 cells treated with sh-EZH2-1, sh-EZH2-2, or sh-EZH2-3, with the lowest expression observed in GIST-T1 cells treated with sh-EZH2-2 (Fig. 1B, C). Here, EZH2 is linked to gastrointestinal stromal tumor.