LMNA and progeroid syndrome: Of note, Lamin A (encoded by lmna) mutations and changes in Lamin A/C expression levels are implicated in many cancers as well as laminopathies associated with progeria, cardiomyopathy and muscular dystrophy (Andrés and González, 2009; Bell and Lammerding, 2016; Dubik and Mai, 2020).