IL10 and atopic eczema: These results are consistent with the pattern of changes in serum levels of IL-10, which are also significantly increased at week 4, with the peak level reached at week 12 after the injections of the same amount of autologous total IgG for the same time period in adult patients with severe atopic dermatitis in our previous study.[25] These results collectively suggest that T cell activation induced by intramuscular administration of autologous total IgG has characteristics of delayed onset and prolonged effect in human subjects.