JUP and gastric cancer: The levels of serum G-17 and PG II in the IN and GC groups were higher than those in the NAG and CAG groups, while the levels of serum PGR were lower than those in the NAG and CAG groups (p ≤ 0.001), indicating that the serum PG I, PG II, and G-17 levels can effectively reflect the condition of the patients’ gastric mucosa and help to improve the diagnosis rate of precancerous lesions and early GC.