The most highly ranked MESA eQTM was cg19103704, which is associated with expression of the proteasome 26S subunit, ATPase 4 (PSMC4), a subunit of perilipin-2 which regulates intracellular lipid metabolism in macrophages, and the fc fragment of IgG binding protein (FCGBP), both of which have been associated with obesity (90, 91). This evidence concerns the gene PLIN2 and Obesity.