PLIN2 and obesity disorder: The most highly ranked MESA eQTM was cg19103704, which is associated with expression of the proteasome 26S subunit, ATPase 4 (PSMC4), a subunit of perilipin-2 which regulates intracellular lipid metabolism in macrophages, and the fc fragment of IgG binding protein (FCGBP), both of which have been associated with obesity (90, 91).