Fung et al. demonstrated that in women compared to men higher plasma Cts (1.30 ± 0.033 vs. 1.14 ± 0.27 nM, p < 0.001) combined with lower CgA precursor concentrations (3.89 ± 0.15 vs. 4.65 ± 0.33 nM, p = 0.006) may be associated with decreased processing of CgA to Cts in the latter (female vs. male Cts/CgA ratio: 26.3 ± 0.006 vs. 23.1 ± 0.006), which predisposes to HT (58). The gene discussed is CGA; the disease is hematocrit.