IL1R1 and COVID-19: Many immune biomarkers have been associated with COVID-19 disease severity, including IL-6, IL-8, IL-10, IL-17A, IL-1RA, IFNγ, GM-CSF, HGF, CCL1, and CXCL13, however, specific roles in neuropathology have not been elucidated for all of them yet (4, 16, 25, 26).