ANPEP and ovarian carcinoma: In conclusion, 68Ga-NGR-RGD demonstrated a promising application for early diagnosis, staging, and follow-up of ovarian cancer, as it showed high tracer uptake, sharp contrasts in subcutaneous xenograft and metastases, and higher tumor-to-background ratios in ovarian tumor models with different expression levels of CD13 and integrin αvβ3, demonstrating superior diagnostic values than 18F-FDG PET/CT.