PDCD1 and acute myeloid leukemia: Patients who achieved CR/CRi were found to have a greater total infiltrative CD3+ T-cell population versus NR who had a significantly higher percentage of CD4 Teff co-expressing PD1/TIM3 (p<0.05), comparable to the TIM3/LAG3 phenotype that in AML that is linked to exhausted immune presentation.