In order to verify the correlation of the expression of the specific pathway-related molecules (SMARCA4, MLH1, TSC1, ATRX, and ATR) with clinical information, we collected microarrays of pancreatic neuroendocrine tumors from 132 tissues, a total of 34 patients, including 30 adjacent tissues and 102 tumor tissues. This evidence concerns the gene ATRX and neuroendocrine neoplasm.