CCND1 and posterior cortical atrophy: Another study found that miR-16 can inhibit PCa cell growth by regulating CDK1 and CDK2, two cell cycle regulatory proteins,300 miR-15a and miR-16-1 have also been shown to affect the survival, growth, and metastasis of PCa cells by triggering CCND1 (encoding cyclin D1) and WNT3A.301