The consistent flow in the ExoSearch chip allows quantitative extraction and release of blood plasma exosomes in a broad range of volumes from 10 mL to 10 L. Using a training set of ovarian cancer plasma samples, they used the ExoSearch chip to perform simultaneous measurements of CA-125, EpCAM, and CD24 (three different exosomal tumor biomarkers) for blood-based ovarian cancer detection. Here, EPCAM is linked to ovarian cancer.