FOXR2 and pineoblastoma: Consistent with this, a recent meta-analysis of studies investigating the molecular features of pineoblastoma identified a 3.3:1 preponderance of males to females in the poor survival PB-MYC/FOXR2 group, where the median age of diagnosis is 1.4 years.29 Notably, in our analysis sex was not associated with prognosis in the older cohort.