AMA: antimitochondrial autoantibodies; ANA: antinuclear antibodies; anti-La/SSB: autoantibodies directed against anti-La/SSB autoantigens; anti-Ro/SSA: autoantibodies directed against Ro/SSA autoantigens; ESR: erythrocyte sedimentation rate; PBC: primary biliary cholangitis; pSS: primary Sjögren's syndrome. This evidence concerns the gene TRIM21 and primary biliary cholangitis.