The plasma expression of CXCL3 in CRC was related to many clinicopathological Characteristics (Table 2) such as tumor size (P = 0.034, Figure 4(a)), staging (P < 0.001, Figure 4(b)), tumor stage (P = 0.003, Figure 4(c)), differentiation (P = 0.001, Figure 4(d)), and lymph node metastasis (P = 0.007, Figure 4(e)), but not sex (P = 0.853, Figure 4(f)), age (P = 0.691, Figure 4(g)), tumor site (P = 1.347Figure 4(h)), or distant metastasis (P = 1.218, Figure 4(i)). This evidence concerns the gene CXCL3 and neoplasm.