When plasma CXCL3 levels were set as the dependent variable, and sex, age, tumor site, tumor size, staging, tumor stage, differentiation, lymph node metastasis, and distant metastasis were set as the independent variables, staging (standard β = 0.773, P = 0.042), tumor stage (standard β = 1.038, P = 0.038), and differentiation (standard β = 1.229, P = 0.024) were found to be independent factors of plasma CXCL3 levels (Table 3). The gene discussed is CXCL3; the disease is metastatic malignant neoplasm in the lymph nodes.