Additionally, miR-214-3p and miR-195-5p, which were predicted to target one or more component genes, have been previously shown to be downregulated in HCC, and to target β-catenin and downstream NF-κB effectors, respectively (Su et al., 2009; Shi et al., 2015). The gene discussed is NFKB1; the disease is hepatocellular carcinoma.