Moreover, the low expression of XDH was associated with poor prognoses in various types of cancers, including colorectal cancer (Linder et al., 2009), early-stage gastric cancer (Linder et al., 2006), breast cancer (Linder et al., 2005), ovarian cancer (Linder et al., 2012), and hepatocellular carcinoma (Chen G.-L. The gene discussed is XDH; the disease is cancer.