However, public RNA-seq datasets indicate that CKB is downregulated in human solid tumors, and its lower expression is associated with a worse prognosis in cervical, head–neck, colon (Mooney et al., 2011), gastric (Mello et al., 2015), kidney, ovarian, pancreatic and sarcoma prostate cancer patients (Wang et al., 2021). The gene discussed is CKB; the disease is sarcoma.