MMP9 and colorectal carcinoma: To further validate the effect of ZEB1-AS1 and SNHG7 on the EMT phenotype in CRC, we detected the expression of EMT-related genes in the transfected cells and found that ZEB1-AS1 and SNHG7 depletion increased the protein level of E-cadherin and decreased the expression of vimentin, N-cadherin, and MMP9 (Figure 12C).