MECP2 and Hepatic fibrosis: In a CCl4-induced liver injury model, Mecp2 null mice show ameliorated liver fibrosis through upregulating the anti-fibrinogenic gene Pparγ61; while, in a bleomycin-induced lung injury model, Mecp2-null mice also show ameliorated lung fibrosis by transcriptionally inactivating the myofibroblast marker a-SMA62.