TRIB1 and cancer: Finally, treatment of MDMs with cancer cell-conditioned medium (CM) also showed a significant overexpression of TRIB1 in these cells (MCM), compared to control (MUN) and MLPS+INF-γ cells (p < 0.05) (Figure 1I), suggesting a potential two-way regulation of TRIB1 expression between BC cells and tumor macrophages.