TRIB1 and breast cancer: Once identified the potential role of TRIB1 in breast cancer outcome and response to therapy, we aimed to characterize TRIB1 protein expression within mammary tumors, using both specimens from human breast cancer (Figure 1E) and a murine model where BC growth was induced in immune-competent, C57BL/6 mice with an orthotropic injection of a murine, Basal-B BC cell line, E0771 37 (Figure 1F).