Compared to size-based isolation and EpCAM-based isolation methods that detected about 20 CTCs as a median value from 7.5 mL of NSCLC patient blood 36-38, CCM-CTCD detected 60 CTCs as a median value from 5.4 mL of blood, almost 4-fold more CTCs, which could be the results that CCM-CTCD isolated various subtypes of CTCs. Here, EPCAM is linked to non-small cell lung carcinoma.