These features were in keeping with the intrinsic erythropoietic failure associated with Diamond Blackfan Anemia (DBA), but both Sanger sequencing and the Multiple Ligand Probe Assay of the genes more frequently associated with DBA (RPS19, RPL5, RPL11, RPS17, RPS26, and RPL35a) did neither reveal any single-nucleotide variants or copy number variants. Here, RPL5 is linked to Diamond-Blackfan anemia.