Any changes or mutations in the STXBP1 gene have been previously reported in link with multiple epileptic encephalopathies along with neurodevelopmental conditions known as infantile epileptic encephalopathy-4 (Saitsu et al., 2008, Milh et al., 2011, Deprez et al., 2010, Otsuka et al., 2010, Vatta et al., 2012, Mignot et al., 2011, Campbell et al., 2012). Here, STXBP1 is linked to Epileptic encephalopathy.