The NF-κB has been previously implicated in ALS (Parisi et al., 2016; Tahamtan et al., 2018; Slota and Booth, 2019; Källstig et al., 2021) and TBI (Jassam et al., 2017; Pierre et al., 2021). This evidence concerns the gene NFKB1 and amyotrophic lateral sclerosis.