Of these, Citrobacter rodentium has been shown to increase the proliferation of colon cancer and to activate cancer promoting biochemical pathways (Umar, 2012), and Haemophilus influenzae has been shown to increase the proliferation of k-ras positive lung adenocarcinoma (Jungnickel et al., 2017). This evidence concerns the gene KRAS and malignant colon neoplasm.