Based on a previous morphometric characterization of IBA1-positive cells in the dACC (Torres-Platas et al., 2014a,b) have suggested an increased density of primed microglia (bigger cell body, ellipsoid-like soma and fewer higher-order branches) in the dACC of individuals with MDD who died by suicide compared to age- and PMI-matched controls. The gene discussed is AIF1; the disease is major depressive disorder.