CDKN1C and cancer: Butyrate is found to downregulate primary miR-17-92a and precursor and mature miR-92a in cancer cells (Hu et al., 2015), which is attributed to the inhibited proliferative and accelerated apoptotic rate via downregulating the oncogene MYC and upregulating CDKN1C (also known as p57), respectively (Hu et al., 2011).