In addition, the prognostic risk prediction model constructed by these five genes could independently predict the prognosis of HER2-positive breast cancer patients, and could be used as a biomarker for patient prognosis.Therefore, on the basis of the current clinical prognosis data, the comprehensive use of the prognostic scoring system can help clinicians to better predict the prognosis of patients, so as to adopt more suitable intervention measures for patients, so as to implement individualized treatment for patients, better treat the patient’s condition. Here, ERBB2 is linked to breast cancer.