In the multivariate logistic analysis, WHR and natural logarithms of FGF21, FGF19, A/L, insulin, albumin, total triglycerides (TG), total cholesterol (TC), and aminotransferase (ALT) were selected as significant independent predictors (rank-ordered by Wald χ2) and used to develop a metabolic stress index for steatosis (MSI-S): ex/(1 + ex) · 100. The gene discussed is FGF19; the disease is steatosis.