The phenotypic spectrum of patients with SCN1A variants included sixteen (72.7%) with DS, two (9.1%) with genetic epilepsy with febrile seizures plus [one evolved into benign epilepsy with centrotemporal spikes (BECTS)], one (4.5%) with focal epilepsy, one (4.5%) with atypical childhood epilepsy with centrotemporal spikes (ABECTS) and two (9.1%) with unclassified epilepsy. This evidence concerns the gene SCN1A and Febrile seizure (within the age range of 3 months to 6 years).