KCNN2 and epilepsy: The inhibition of CK2 by 4,5,6,7-tetrabromotriazole in acute epilepsy slice models resulted in increased expression of HCN1 channels, HCN3 channels, and voltage-independent calcium (Ca2+)-activated potassium (K+) channels (KCa2.2), also known as small-conductance Ca2+-activated K+ channels (SK2), thereby producing antiepileptic effects (Schulze et al., 2020).