Previous studies have shown that mutations of the GABA receptors, such as, GABRA1, GABRA5, GABRA6, GABRB3, GABRD, GABRG2, were associated with idiopathic generalized epilepsy (Cossette et al., 2002; Hirose, 2006; Moller et al., 2017; Lee et al., 2018; May et al., 2018). Here, GABRB3 is linked to idiopathic generalized epilepsy.